Bioengineered tooth response to mechanical stress
It is well known that an alveolar bone remodeling was induced via the response of periodontal ligament according to a mechanical stress such as the treatment of orthodontic movement. Previous studies demonstrated that the localizations of osteoclast for bone absorption in compression side and osteoblast for bone formation in tension side were observed. Thus, we analyzed the tooth movement and localizations of osteoclast and osteoblast for bone remodeling in alveolar bone by an experimental orthodontic movement. A normal tooth and the bioengineered tooth was moved buccally for 17 days with a mechanical force. At 6 days after the treatment, histochemical analysis revealed that morphological changes of periodontal ligament were observed in both the lingual tensioned side and buccal compressed side. The bioengineered tooth could successfully moved in response to the mechanical stress as well as normal tooth.
